Protein Phosphatase 2C from bovine brain
SIGMA/P1743 - buffered aqueous glycerol solution
CAS Number: 362690-38-8
MDL Number: MFCD04041076
Product Type: Chemical
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| assay | >90% (SDS-GE) |
| biological source | bovine brain |
| form | buffered aqueous glycerol solution |
| mol wt | 42-45 kDa |
| packaging | vial of 1 μg |
| Quality Level | 200  |
| shipped in | dry ice |
| specific activity | ~1000 units/mg protein |
| storage temp. | −70°C |
| technique(s) | ligand binding assay: suitable |
| UniProt accession no. | P67774  |
| Biochem/physiol Actions: | In Arabidopsis, protein phosphatase 2C (PP2C) negatively regulates plant hormone, abscisic acid (ABA) signal transduction. In eukaryotes, this protein modulates the cell cycle by reversing the activating phosphorylation of cyclin-dependent protein kinases (CDKs). PP2C acts as a crucial physiological regulators of cell growth and of cellular stress signaling. |
| General description: | Protein phosphatase 2C (PP2C) is a member of protein phosphatases, Mg2+/Mn2+ dependent (PPM) family. PP2C is a monomeric enzymes found in both prokaryotes and eukaryotes. |
| Other Notes: | One unit will release 1.0 nanomole of phosphate from 32P-labeled myelin basic protein at pH 7.0 at 30 °C |
| Physical form: | Solution in 50 mM Tris-HCl, pH 7.0, containing 14 mM 2-mercaptoethanol, 1 mM benzamidine, 0.1 mM PMSF, 1 mM EDTA, and 50% glycerol |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H317 |
| Precautionary statements | P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >90% (SDS-GE) |
| activity | specific activity: ~1000 units/mg protein |
| Storage Temp. | −70°C |
| UNSPSC | 12352202 |