trans-2-Phenylcyclopropylamine hemisulfate salt

SIGMA/P1761

Synonym: Tranylcypromine

CAS Number: 13492-01-8
Empirical Formula (Hill Notation): C₉H₁₁N · 0.5H₂O₄S
Molecular Weight: 182.23
EC Number: 236-807-1
MDL Number: MFCD00079222
Linear Formula: C₉H₁₁N · 1/2H₂SO₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-P1761-25G	25 g	$724.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (perchloric acid titration)
form	powder
InChI	1S/2C9H11N.H2O4S/c210-9-6-8(9)7-4-2-1-3-5-7;1-5(2,3)4/h21-5,8-9H,6,10H2;(H2,1,2,3,4)/t2*8-,9+;/m11./s1
InChI key	BKPRVQDIOGQWTG-KAVFMPKWSA-N
Quality Level	200
SMILES string	OS(O)(=O)=O.N[C@H]1C[C@@H]1c2ccccc2.N[C@H]3C[C@@H]3c4ccccc4
solubility	water: 0.0333 g/mL, clear to slightly hazy, colorless to faintly yellow
storage temp.	2-8°C

Biochem/physiol Actions:	trans-2-Phenylcyclopropylamine acts as an inhibitor of lysine-specific demethylase 1 (LSD1). It exhibits anti-depressant and anxiolytic activity. Tranylcypromine shows therapeutic effects against mood and anxiety issues. It also exhibits anti-osteoclastogenic effects through monoamine oxidase-A (MAO-A). Tranylcypromine may play a role in bone remodeling in mice.
Biochem/physiol Actions:	Non-selective MAO-A/B inhibitor.

Symbol	GHS06
Signal word	Danger
Hazard statements	H300 - H311 + H331
Precautionary statements	P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
Hazard Codes	T
Risk Statements	23/24/25
Safety Statements	36/37/39-45
RIDADR	UN 2811 6.1 / PGII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (perchloric acid titration)
Storage Temp.	2-8°C
UNSPSC	12352116

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