PIPES

SIGMA/P1851 - BioPerformance Certified, suitable for cell culture

Synonym: 1,4-Piperazinediethanesulfonic acid; Piperazine-1,4-bis(2-ethanesulfonic acid); Piperazine-N,N′-bis(2-ethanesulfonic acid)

CAS Number: 5625-37-6
Empirical Formula (Hill Notation): C₈H₁₈N₂O₆S₂
Molecular Weight: 302.37
EC Number: 227-057-6
MDL Number: MFCD00006159
Linear Formula: C₈H₁₈N₂O₆S₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-P1851-25G	25 g	$44.90 1/EA	Add To Favorites
45-P1851-100G	100 g	$141.00 1/EA	Add To Favorites
45-P1851-500G	500 g	$571.00 1/EA	Add To Favorites
45-P1851-1KG	1 kg	$1010.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: P1851-100G

Properties
Descriptions
Safety Info.
Basic Data

application(s)	diagnostic assay manufacturing
foreign activity	DNAse, Exonuclease; NICKase, Endonuclease; RNAse; Protease, none detected
form	crystalline powder
grade	BioPerformance Certified
	Molecular Biology
impurities	endotoxin and Total Aerobic Microbial Count, tested
InChI	1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)
InChI key	IHPYMWDTONKSCO-UHFFFAOYSA-N
mp	>300 °C (lit.)
pKa (25 °C)	6.8
Quality Level	400
SMILES string	OS(=O)(=O)CCN1CCN(CC1)CCS(O)(=O)=O
solubility	1 M NaOH: 20 + 80 mL g, clear, colorless
	soluble
technique(s)	cell culture \| mammalian: suitable
useful pH range	6.1-7.5

Application:	Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics.: The use of PIPES buffer in this study was integral to maintaining the stability of immunoglobulin G during differential scanning fluorimetry. This method is crucial for evaluating the stability of antibody-based therapeutics (Moggridge et al., 2017 ).
Packaging:	1 kg in poly bottle
Packaging:	100, 500 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

mp	>300 °C (lit.)
UNSPSC	12161700

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