Protein Phosphatase 2A2 from bovine kidney
SIGMA/P1868 - buffered aqueous glycerol solution
Synonym: PP2A2
Product Type: Chemical
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| biological source | bovine kidney |
| form | buffered aqueous glycerol solution |
| mol wt | dimer 101 kDa (65 kDa and 36 kDa) |
| Quality Level | 200  |
| shipped in | dry ice |
| specific activity | ~2.0 U/vial |
| storage temp. | −70°C |
| Application: | Protein phosphatase 2A2 has been used in a study to investigate two heat-stable protein inhibitors. It has also been used in a study to describe the purification and properties of a protamine kinase from bovine kidney microsomes. |
| Biochem/physiol Actions: | Protein Phosphatase 2A2 from bovine kidney was shown to be a unique inhibitor of protamine kinase while other phosphatases in the same family including PP1, PP2B, PP2C did not show any inhibition. |
| General description: | Protein phosphatase 2A (PP2A) is a specific protamine-kinase-inactiva |
| Other Notes: | One unit will release 1 nanomole of inorganic phosphate from (32)P-labeled phosphorylase per minute at pH 7.0 at 30 deg C. |
| Physical form: | Solution of 1 μg per vial in 50 μl of 50 mM Tris-HCl, pH 7.0, containing 14 mM β-Mercaptoethanol, 1mM benzamidine, 0.1 mM PMSF, 1mM EDTA, and 50% glycerol. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H317 |
| Precautionary statements | P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: ~2.0 U/vial |
| Storage Temp. | −70°C |
| UNSPSC | 12352204 |