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PEAQX tetrasodium hydrate

SIGMA/P1999 - ≥98% (HPLC)

Synonym: NVP-AAM077 tetrasodium hydrate; [[[(1S)-1-(4-Bromophenyl)ethyl]amino](1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl] phosphonic acid tetrasodium hydrate

CAS Number: 459836-30-7 (free base)
Empirical Formula (Hill Notation): C17H13BrN3Na4O5P · xH2O
Molecular Weight: 542.14 (anhydrous basis)
Linear Formula: C17H13BrN3Na4O5P · xH2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P1999-5MG 5 mg
 $234.00
1/EA		 Add To Favorites
45-P1999-25MG 25 mg
 $817.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C17H17BrN3O5P.4Na.H2O/c1-9(10-5-7-11(18)8-6-10)19-17(27(24,25)26)12-3-2-4-13-14(12)21-16(23)15(22)20-13;;;;;/h2-9,17,19H,1H3,(H,20,22)(H,21,23)(H2,24,25,26);;;;;1H2/q;4*+1;/p-4/t9-,17?;;;;;/m0...../s1
InChI key SMGAGBKXHAHCGQ-VSYRWHDMSA-J
Quality Level 100 
SMILES string [Na+].[Na+].[Na+].[Na+].[H]O[H].C[C@H](NC(c1cccc2nc([O-])c([O-])nc12)P([O-])([O-])=O)c3ccc(Br)cc3
solubility water: 10 mg/mL
storage condition desiccated
storage temp. −20°C
Application: PEAQX tetrasodium hydrate has been used N-methyl-D-aspartate (NMDA) receptor 2A (NR2A) antagonist in rats and mice.
Biochem/physiol Actions: NMDA receptor antagonist.
Biochem/physiol Actions: PEAQX is more specific for N-methyl-D-aspartate (NMDA) receptor 2A (NR2A) than N-methyl-D-aspartate (NMDA) receptor 2B (NR2B) and induces striatal apoptosis. It is less potent in activating caspase-3 than its stereomer NVP-AAM007.
Features and Benefits: This compound is a featured product for Neuroscience research. Click here  to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the Glutamate Receptors (Ion Channel Family)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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