Poly-L-proline

SIGMA/P2254 - mol wt 1,000-10,000

Synonym: L-Proline homopolymer

CAS Number: 25191-13-3
Empirical Formula (Hill Notation): C₅H₉NO₂
Molecular Weight: 115.13
MDL Number: MFCD00166364
Linear Formula: C₅H₉NO₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-P2254-50MG	50 mg	$346.00 1/EA	Add To Favorites
45-P2254-100MG	100 mg	$589.00 1/EA	Add To Favorites
45-P2254-500MG	500 mg	$1300.00 1/EA	Add To Favorites
45-P2254-1G	1 g	$2040.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: P2254-1G

Properties
Descriptions
Safety Info.
Basic Data

color	white
form	powder
InChI	1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)
InChI key	ONIBWKKTOPOVIA-UHFFFAOYSA-N
mol wt	1,000-10,000
Quality Level	200
SMILES string	OC(=O)C1CCCN1
storage temp.	−20°C
technique(s)	ligand binding assay: suitable

Analysis Note:	Molecular weight based on viscosity.
Application:	Highly sensitive and selective electrochemical sensor for simultaneous determination of gallic acid, theophylline and caffeine using poly(l-proline) decorated carbon nanotubes in biological and food samples.: This study presents an innovative electrochemical sensor that utilizes poly-L-proline decorated carbon nanotubes for the simultaneous detection of gallic acid, theophylline, and caffeine. This sensor demonstrates high sensitivity and selectivity, making it suitable for applications in both biological and food samples (Aschemacher NA et al., 2024 ). Water-assisted and protein-initiated fast and controlled ring-opening polymerization of proline N-carboxyanhydride.: This research explores the water-assisted and protein-initiated ring-opening polymerization of proline N-carboxyanhydride, leading to the rapid and controlled synthesis of poly-L-proline. The study highlights the method′s efficiency and potential for producing high-quality poly-L-proline for various applications (Hu Y et al., 2022 ). Phosphorylation of the actin-binding protein profilin2a at S137 modulates bidirectional structural plasticity at dendritic spines.: This study examines the role of poly-L-proline regions in the actin-binding protein profilin2a, specifically focusing on its phosphorylation at S137. The findings reveal how these modifications impact the structural plasticity of dendritic spines, providing insights into neuronal function and plasticity (Cornelius J et al., 2023 ). A structural model of the profilin-formin pacemaker system for actin filament elongation.: This paper presents a structural model involving poly-L-proline regions within the profilin-formin complex, which acts as a pacemaker for actin filament elongation. The study offers a detailed understanding of the molecular mechanisms driving actin dynamics and cellular movement (Schutt CE et al., 2022 ).
Biochem/physiol Actions:	Poly-L-Proline is an antigenic homopolymer.
Other Notes:	For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource .
Packaging:	1 g in poly bottle
Packaging:	50, 100, 500 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	−20°C
UNSPSC	12352209

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