Protein Kinase G II from rat
SIGMA/P2363 - >90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf9 cells, solution
Synonym: Protein Kinase, 3′,5′-Cyclic GMP Dependent from rat
MDL Number: MFCD03444648
Product Type: Chemical
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| assay | >90% (SDS-PAGE) |
| form | solution |
| Quality Level | 200  |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| specific activity | ~0.7 U/mg |
| storage temp. | −20°C |
| UniProt accession no. | Q64595  |
| Biochem/physiol Actions: | Protein kinase, cGMP-dependent, type II (PRKG2) is implicated in the regulation of intestinal fluid balance in man. The encoded protein plays an essential role in proliferative to hypertrophic transition of growth plate chondrocytes during endochondral ossification. Loss of PRKG2 function is associated with the development of renal cysts, intellectual disability and speech defect. In rodent and bovine models, deletion of the gene leads to dwarfism. |
| General description: | Protein kinase, cGMP-dependent, type II (PRKG2), also known as type II cGMP-dependent protein kinase (cGK), is encoded by the gene mapped to human chromosome 4q13.1–q21.1. |
| Other Notes: | One unit will phosphorylate one μmole of VASPtide (RRKVSKQE) per minute at pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >90% (SDS-PAGE) |
| activity | specific activity: ~0.7 U/mg |
| Storage Temp. | −20°C |
| UNSPSC | 41106305 |