Phytosphingosine hydrochloride
SIGMA/P2795
Synonym: 4-Hydroxysphinganine; D-
CAS Number: 554-62-1
Empirical Formula (Hill Notation): C18H39NO3 · HCl
Molecular Weight: 353.97
MDL Number: MFCD06804643
Linear Formula: C18H39NO3 · HCl
Product Type: Chemical
12 Principles of Green Chemistry: Principle 3—Less Hazardous Chemical Syntheses. This product manufacturing process was designed with lesser toxicity to human health and the environment.
12 Principles of Green Chemistry: Principle 5—Safer Solvents and Auxiliaries. This product utilizes reduced volumes of auxiliary substances that are less hazardous.
12 Principles of Green Chemistry: Principle 7—A raw material or feedstock should be renewable rather than depleting whenever technically and economically practicable.
| form | powder |
| greener alternative category |  , Re-engineered |
| greener alternative product characteristics | Less Hazardous Chemical Syntheses Safer Solvents and Auxiliaries Use of Renewable Feedstocks Learn more about the Principles of Green Chemistry . |
| greener alternative product score | old score: 19 new score: 9 Find out more about DOZN™ Scoring |
| InChI | 1S/C18H39NO3.ClH/c1-2-3-4 |
| InChI key | GDKAAHDFPOWGQE-RXQQAGQTSA |
| lipid type | sphingolipids |
| Quality Level | 200 |
| SMILES string | Cl.CCCCCCCCCCCCCC[C@@H](O |
| storage temp. | −20°C |
| sustainability | Greener Alternative Product |
| Biochem/physiol Actions: | Phytosphingosine is a long chain sphingoid base that occurs broadly in yeast, plants and animals including mammals. In yeast it is involved in mediating the heat stress response, perhaps through activation of the AGC-type protein kinases, Pkh1, Pkh2, Ypk1, Ypk2, and Sch9. It is proapoptotic in human cancer cell lines. PHS induces ΔΨm and release of cytochrome c from mitochondria either directly or through activation of p38 MAPK pathway. This leads to activation of caspase 9 followed by activation of caspase 3 and programmed cell death. |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352211 |