Phenylarsine oxide
SIGMA/P3075 - ≥97%, powder
Synonym: Arzene; Oxophenylarsine; PAO
CAS Number: 637-03-6
Empirical Formula (Hill Notation): C6H5AsO
Molecular Weight: 168.02
EC Number: 211-275-3
MDL Number: MFCD00001990
Linear Formula: C6H5AsO
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P3075-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P3075-5G
| assay | ≥97% |
| biological source | synthetic (organic) |
| color | white to off-white |
| form | powder |
| InChI | 1S/C6H5AsO/c8-7-6-4-2-1-3 |
| InChI key | BQVCCPGCDUSGOE-UHFFFAOYSA |
| mp | 145-148 °C |
| Quality Level | 100  |
| SMILES string | O=[As]c1ccccc1 |
| solubility | DMSO: 50 mg/mL |
| Application: | Phenylarsine oxide has been used to infuse animals with a nigrostriatal transection, to determine whether peroxovanadium (pVa) would synergize with brain-derived neurotrophic factor (BDNF). |
| Biochem/physiol Actions: | Phenylarsine oxide inhibits internalization of cell surface receptors; inhibits tyrosine phosphatases, with no effect on tyrosine kinase. Metabolic poison. |
| Biochem/physiol Actions: | Phenylarsine oxide (PAO) can reduce the motility and sustainability of Setaria cervi. It has the ability to stimulate cyclosporin A-sensitive transition in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid). It acts as a stimulator of mitochondrial ion fluxes. |
| Features and Benefits: | This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| General description: | Phenylarsine oxide (PhAsO4) is a bifunctional SH group chemical. It is hydrophobic in nature. |
| Packaging: | 1, 5 g in glass bottle |
| Symbol |   GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H301 + H331 - H410 |
| Precautionary statements | P273 - P301 + P310 + P330 - P304 + P340 + P311 |
| Hazard Codes | T,N |
| Risk Statements | 23/25-50/53 |
| Safety Statements | 20/21-28-45-60-61 |
| RIDADR | UN 3465 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% |
| mp | 145-148 °C |
| UNSPSC | 12352119 |