Penfluridol

SIGMA/P3371 - ≥97% (HPLC), powder

Synonym: 1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3(trifluoromethyl)phenyl]-4-piperidinol; R16341

CAS Number: 26864-56-2
Empirical Formula (Hill Notation): C₂₈H₂₇ClF₅NO
Molecular Weight: 523.97
EC Number: 248-074-5
MDL Number: MFCD00866714
Linear Formula: C₂₈H₂₇ClF₅NO
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-P3371-50MG	50 mg	$202.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (HPLC)
color	white
form	powder
InChI	1S/C28H27ClF5NO/c29-26-12-7-21(18-25(26)28(32,33)34)27(36)13-16-35(17-14-27)15-1-2-24(19-3-8-22(30)9-4-19)20-5-10-23(31)11-6-20/h3-12,18,24,36H,1-2,13-17H2
InChI key	MDLAAYDRRZXJIF-UHFFFAOYSA-N
originator	Johnson & Johnson
Quality Level	100
SMILES string	OC1(CCN(CCCC(c2ccc(F)cc2)c3ccc(F)cc3)CC1)c4ccc(Cl)c(c4)C(F)(F)F
solubility	DMSO: >20 mg/mL
	H₂O: insoluble
storage temp.	2-8°C

Application:	Penfluridol has been used as an antipsychotic agent: • to study its antimetastatic effect on triple-negative breast cancer cells • to study its effects on the growth of glioblastoma cell lines, • to study its effects on the vascular endothelial growth factor (VEGF)-induced angiogenesis in human umbilical vein endothelial cells (HUVECs)
Biochem/physiol Actions:	Penfluridol is studied in the treatment of schizophrenia, Tourette syndrome and acute psychosis. It also exhibits anticancer activity.
Biochem/physiol Actions:	T-type Ca²⁺channel blocker; antipsychotic
Features and Benefits:	This compound was developed by Johnson & Johnson . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging:	50 mg in glass bottle

Symbol	GHS06
Signal word	Danger
Hazard statements	H301
Precautionary statements	P301 + P310
Hazard Codes	T
Risk Statements	25
Safety Statements	45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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