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5β-Pregnane-3α,20α-diol glucuronide

SIGMA/P3635

Synonym: P3G; PDG; Pn3-G; Pregnanediol-3a-glucuronide; Pregnanediol-glucuronide; 3α,20α-Dihydroxy-5β-pregnane 3-glucuronide

CAS Number: 1852-49-9
Empirical Formula (Hill Notation): C27H44O8
Molecular Weight: 496.63
MDL Number: MFCD00056522
Linear Formula: C27H44O8
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P3635-5MG 5 mg
 $435.00
1/EA		 Add To Favorites
45-P3635-25MG 25 mg
 $1730.00
1/EA		 Add To Favorites

 

assay ≥98.00% (TLC)
form powder
InChI 1S/C27H44O8/c1-13(28)17-6-7-18-16-5-4-14-12-15(8-10-26(14,2)19(16)9-11-27(17,18)3)34-25-22(31)20(29)21(30)23(35-25)24(32)33/h13-23,25,28-31H,4-12H2,1-3H3,(H,32,33)
InChI key ZFFFJLDTCLJDHL-UHFFFAOYSA-N
Quality Level 200 
shipped in ambient
SMILES string CC(O)C1CCC2C3CCC4CC(CCC4(C)C3CCC12C)OC5OC(C(O)C(O)C5O)C(O)=O
solubility ethanol: 20 mg/mL, clear, colorless
sterility non-sterile
storage temp. −20°C
technique(s) enzyme immunoassay: suitable
Application: 5β-Pregnane-3α,20α-diol glucuronide has been used in a cross-sectional analysis of hormone levels. It has also been used as a standard to measure estradiol-17β, pregnanediol-glucuronide (PdG) by a double-antibody enzyme immunoassay.
Application: 5β-Pregnane-3α,20α-diol glucuronide has been used in steroid enzyme immunoassay.
General description: 5β-Pregnane-3α,20α-diol glucuronide is a progesterone metabolite predominant in urine, during pregnancy. Presence of 5β-Pregnane-3α,20α-diol glucuronide in the urine indicates pregnancy, but it might also account for pseudopregnancy. It is useful in predicting the delivery time/end of pseudopregnancy.
General description: Urinary pregnanediol glucuronide (PdG) seems to serve as an effective clinical marker for monitoring progesterone supplementation. PdG, along with other urinary metabolites such as luteinizing hormone (LH), follicle stimulating hormone (FSH), and estrone glucuronide (ElG), exhibit a strong association with ovarian excretion rates and demonstrate a high correlation with serum reproductive hormones. As a result, they can be used interchangeably to effectively monitor ovarian steroidogenesis.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98.00% (TLC)
Storage Temp. −20°C
UNSPSC 51111800

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