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6-Propyl-2-thiouracil

SIGMA/P3755 - enzyme inhibitor

Synonym: 2,3-Dihydro-6-propyl-2-thioxo-4(1H)-pyrimidinone; 4-Hydroxy-2-mercapto-6-propylpyrimidine

CAS Number: 51-52-5
Empirical Formula (Hill Notation): C7H10N2OS
Molecular Weight: 170.23
EC Number: 200-103-2
MDL Number: MFCD00006041
Linear Formula: C7H10N2OS
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P3755-10G 10 g
 $64.80
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45-P3755-25G 25 g
 $101.00
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45-P3755-100G 100 g
 $326.00
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FT-NMR Spectra for 2,3-Dihydro-6-propyl-2-thioxo-4(1H)-pyrimidinone.
FT-IR Spectra for 2,3-Dihydro-6-propyl-2-thioxo-4(1H)-pyrimidinone.

 

assay ≥99% (HPLC)
description enzyme inhibitor
form powder
InChI 1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)
InChI key KNAHARQHSZJURB-UHFFFAOYSA-N
mp 218-220 °C (lit.)
Quality Level 200 
SMILES string CCCC1=CC(=O)NC(=S)N1
solubility 10% NH3: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
Application: 6-Propyl-2-thiouracil (PROP) has been used to impregnate on disk for PROP taster status studies for sensory characterization in a defined human sample group. It has been used as a screening agent for testing the intensity of taste by labeled magnitude scale (LMS).
Application: 6-Propyl-2-thiouracil is a thyreostatic (thyroid hormone) agent that may be used as a reference material in thyreostatic drug separation and detection technologies such as capillary electrophoresis, high performance liquid chromatography (HPLC), or gas chromatography.
Biochem/physiol Actions: 6-Propyl-2-thiouracil (6-PTU), a potential inhibitor of D1 iodothyronine deiodinase, is involved in the deiodination of iodothyronines. It is an uncompetitive inhibitor of iodothyronine substrates.
General description: 6-Propyl-2-thiouracil or 6-n-Propylthiouracil (PROP) is a compound with a bitter taste.
Packaging: 10, 25, 100 g in glass bottle
Purity ≥99% (HPLC)
mp 218-220 °C (lit.)
UNSPSC 41106305

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