L-α-Phosphatidylcholine
SIGMA/P3782 - solution, from soybean, suitable for cell culture, Type III-S
Synonym: 1,2-Diacyl-sn-
CAS Number: 8002-43-5
Product Type: Chemical
| assay | ≥98% |
| biological source | soybean |
| concentration | 100 mg/mL in chloroform |
| form | solution |
| InChI | 1S/C42H80NO8P/c1-6-8-10-1 |
| InChI key | JLPULHDHAOZNQI-ZTIMHPMXSA |
| Quality Level | 200  |
| SMILES string | [P](=O)([O-])(OC[C@H](OC( |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| type | Type III-S (III is the third type of Phosphatidylcholines produced; S is for Soybean.) |
| Application: | L-α-Phosphatidylcholine has been used in phospholipid solid phase enzyme-linked immunosorbent assay (ELISA) to test its interaction with Factor VIII variants (N0 and N6). It has also been used in the synthesis of phosphatidylcholine hydroperoxide (PCOOH) substrate for the glutathione peroxidase (GPx4) assay. |
| Biochem/physiol Actions: | A major structural phospholipid in brain, comprising approx. 15% of total lipid; primarily localized to gray matter. |
| Biochem/physiol Actions: | Phosphatidylcholine is essential for acetylcholine synthesis and is crucial for very-low-density lipoprotein secretion in hepatocytes. The pathophysiology of non-alcoholic fatty liver disease (NAFLD) displays a variation in the hepatic PC to phosphatidylethanolamine (PE) ratio. PC alleviates inflammation in ulcerative colitis (UC) and its administration is effective for treating benign symmetric lipomatosis. |
| General description: | Phosphatidylcholine is a phospholipid comprising a choline head group and is associated with organelle membrane and cytomembrane. |
| Packaging: | 50, 100, 500 mg in serum bottle |
| Preparation Note: | Prepared Chromatographically. Prepared by a modification of the procedure of Singleton, W.S., et al., J. Am. Oil Chem. Soc., 42, 53 (1965). |
| Symbol |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 |
| Precautionary statements | P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 63-20/22-36/38-40-48/20/22 |
| Safety Statements | 26-36/37 |
| RIDADR | UN 1888 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| Storage Temp. | −20°C |
| UNSPSC | 12352211 |