20S Proteasome Fraction from rabbit
SIGMA/P3988 - ≥95% (SDS-PAGE), solution
MDL Number: MFCD01091499
Product Type: Chemical
ATP-independent catalytic core of the 26S proteasome.
A polyubiquitin tagged protein targeted degradation is is hydrolyzed by the 26S proteasome in an ATP-dependent process, and free ubiquitin is released. The 20S proteasome is the ATP-independent catalytic core of the 26S proteasome.
| application(s) | cell analysis |
| assay | ≥95% (SDS-PAGE) |
| biological source | rabbit |
| form | solution |
| mol wt | 700 kDa |
| Quality Level | 200  |
| shipped in | dry ice |
| storage temp. | −70°C |
| UniProt accession no. | A0A5F9CPK4  |
| G1SU71 |
| Application: | 20S proteasome fraction from rabbit has been used as a positive control to determine proteasome activity. |
| Biochem/physiol Actions: | Catalytic core of the 26S proteasome that degrades polyubiquitinated proteins. |
| Biochem/physiol Actions: | Hydrolyzes various peptide substrates and proteins with broad specificity in a non-ATP dependent process. |
| General description: | Manufactured for Sigma by Boston Biochem., Inc. |
| Physical form: | Solution in 50 mM HEPES, pH 7.6, 150 mM sodium chloride, and 1 mM DTT, pH 7.6. |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352202 |