Protamine from salmon
SIGMA/P4005 - Grade IV, Histone, free(Millon test)
Synonym: Protamine
CAS Number: 9012-00-4
EC Number: 232-726-0
MDL Number: MFCD00132089
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P4005-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P4005-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P4005-250MG
| biological source | fish (salmon) |
| form | solid |
| impurities | Histone, free (Millon test) |
| Quality Level | 200  |
| solubility | H2O: soluble, clear to slightly hazy, colorless to faintly yellow |
| storage temp. | −20°C |
| type | Grade IV |
| Application: | Protamine from salmon has been used to avoid in vitro AT complex formation in samples from dogs pre-treated with heparin. It has also been used to study the influences of external potential on adsorption of various proteins to a metal surface. |
| Biochem/physiol Actions: | Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1. |
| Biochem/physiol Actions: | Protamines are found to displace histones in DNA during spermatogenesis in animals and plants. Protamine is useful as a heparin neutralizer during heart surgery, dialysis and in many other clinical procedures. |
| General description: | Protamines are proteins rich in cysteine and arginine. It possesses many phosphorylation sites. Salmon fish contains around 15 genes encoding protamine. It is found to be localized to the sperm head. |
| Packaging: | 1, 5 g in poly bottle |
| Packaging: | 250 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |