Polyinosinic acid potassium salt
SIGMA/P4154 - Homopolymer
Synonym: Poly(I) potassium salt
CAS Number: 26936-41-4
MDL Number: MFCD00131982
Product Type: Chemical
Polyinosinic acid potassium salt unit structure.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P4154-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P4154-10MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P4154-25MG
| assay | ≥98% (TLC) |
| biological source | synthetic (organic) |
| form | lyophilized powder |
| Quality Level | 200  |
| solubility | water: 4.80-5.20 mg/mL, clear to hazy, colorless to faintly yellow |
| storage temp. | −20°C |
| Application: | Polyinosinic acid (Poly(I)) is a homopolymer of inosine that may be used with polycytidylic acid (poly(C)) to form the double-stranded homopolymer (Poly(I) • Poly(C)). TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. (Poly(I) • Poly(C)) is a used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand. |
| Packaging: | 10, 25, 100 mg in poly bottle |
| Preparation Note: | Prepared from IDP using polynucleotide phosphorylase. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (TLC) |
| Storage Temp. | −20°C |
| UNSPSC | 41106305 |