Synonym: 2-(4-Methylphenyl)imidazo[2,1-b]-5,6,7,8-tetrahydrobenzothiazole hydrobromide; Cyclic PFT-α hydrobromide; Pifithrin-α, cyclic; QB102
CAS Number: 511296-88-1
Empirical Formula (Hill Notation): C16H16N2S · HBr
Molecular Weight: 349.29
MDL Number: MFCD02683960
Linear Formula: C16H16N2S · HBr
Product Type: Chemical
| assay |
≥98% (HPLC) |
| form |
solid |
| InChI |
1S/C16H16N2S.BrH/c1-11-6-8-12(9-7-11)13-10-18-14-4-2-3-5-15(14)19-16(18)17-13;/h6-10H,2-5H2,1H3;1H |
| InChI key |
SGNCOAOESGSEOP-UHFFFAOYSA-N |
| Quality Level |
100  |
| shipped in |
dry ice |
| SMILES string |
Br[H].Cc1ccc(cc1)-c2cn3c4CCCCc4sc3n2 |
| solubility |
DMSO: 20 mg/mL |
| storage condition |
desiccated |
| storage temp. |
−20°C |
| Application: |
Cyclic Pifithrin-α hydrobromide has been used as p53 inhibitor to study its role in cigarette smoke−induced apoptosis of pulmonary endothelial cells. |
| Biochem/physiol Actions: |
A stable analog of Pifithrin-α (Product Code P4359) with similar biological activities and lower cellular toxicity. |
| Packaging: |
5, 10 mg in glass bottle |
| Packaging: |
Protect from light. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
−20°C |
| UNSPSC |
12352200 |
