Protamine sulfate salt from salmon
SIGMA/P4380 - Grade II
Synonym: Salmine; Salmine from salmon
CAS Number: 53597-25-4
MDL Number: MFCD00132091
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P4380-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P4380-25G
| biological source | fish (salmon) |
| color | white to off-white |
| form | powder |
| Quality Level | 200  |
| solubility | 6 M HCl: 25 mg/mL, clear, colorless to light yellow |
| type | Grade II |
| Analysis Note: | May contain insolubles as well as histones. |
| Application: | May be used for the removal of DNA from protein samples or for the purification of DNA binding proteins. It may be used as an alternative to polybrene in retroviral-mediated gene transfer. Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1. |
| Application: | Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1. |
| Application: | Protamine sulfate salt from salmon has been used in the generation of protamine silica nanocomposites. |
| Biochem/physiol Actions: | Protamine sulfate is a small cationic protein that binds and precipitates DNA. Neutralizes the anticoagulant activity of heparin. Inhibits lipoprotein lipase. |
| Biochem/physiol Actions: | Protamine sulfate is highly preferred in cardiovascular surgical procedures to reverse the anticoagulant propert |
| General description: | Protamine sulfate (PS), a polycationic, positively charged protein is mostly made up of poly(l-arginine). It is obtained from salmon sperm protein. |
| Packaging: | 25, 100 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352202 |