Podophyllotoxin
SIGMA/P4405
CAS Number: 518-28-5
Empirical Formula (Hill Notation): C22H22O8
Molecular Weight: 414.41
EC Number: 208-250-4
MDL Number: MFCD00075290
Linear Formula: C22H22O8
Product Type: Chemical
| assay | ≥98% |
| form | powder |
| InChI | 1S/C22H22O8/c1-25-16-4-10 |
| InChI key | YJGVMLPVUAXIQN-XVVDYKMHSA |
| mp | 183-184 °C (lit.) |
| Quality Level | 200 ![]() |
| SMILES string | COc1cc(cc(OC)c1OC)[C@H]2C |
| storage temp. | 2-8°C |
| Application: | Podophyllotoxin has been used as a reference compound for evaluating the cytotoxicity in VERO cells. It has also been used as a reference standard in high-performance liquid chromatography (HPLC). |
| Biochem/physiol Actions: | Inhibits microtubule assembly; antineoplastic. |
| Biochem/physiol Actions: | Podophyllotoxin is a naturally occurring lignan obtained from resin podophyllin present in the genus Podophyllum. It exhibits antiviral and antimitotic properties. Podophyllotoxin may be used to treat anogenital warts in children and dermatological conditions caused by psoriasis vulgaris. It may also be used as a therapeutic agent to treat genital tumors, Wilms tumors, lung cancer, and lymphomas. |
| Packaging: | 100 mg in glass bottle |
| Packaging: | 50 mg in poly bottle |
| Symbol | GHS06 |
| Signal word | Danger |
| Hazard statements | H301 + H311 + H331 - H315 - H319 - H335 |
| Precautionary statements | P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338 |
| Hazard Codes | T |
| Risk Statements | 21-25-36/37/38 |
| Safety Statements | 36/37/39-45 |
| RIDADR | UN 3462 6.1 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| mp | 183-184 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |


