Synonym: (βR, δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β, δ,6-trihydroxy-2-methyl-8[(2S)-2-methyl-1-oxobutoxyl]-1-naphthaleneheptanoic acid sodium hydrate; Eptastatin sodium salt hydrate
CAS Number: 81131-70-6 (anhydrous)
Empirical Formula (Hill Notation): C23H35O7Na · xH2O
Molecular Weight: 446.51 (anhydrous basis)
MDL Number: MFCD00887601
Linear Formula: C23H35O7Na · xH2O
Product Type: Chemical
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This image depicts P4498-25MG.
| assay |
≥98% (HPLC) |
| biological source |
synthetic (organic) |
| color |
white |
| form |
powder |
| InChI |
1S/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1 |
| InChI key |
VWBQYTRBTXKKOG-IYNICTALSA-M |
| mp |
171.2-173 °C |
| originator |
Bristol-Myers Squibb |
| Quality Level |
100  |
| SMILES string |
[Na+].[H][C@@](O)(CC[C@H]1[C@@H](C)C=CC2=C[C@@H](O)C[C@H](OC(=O)[C@@H](C)CC)[C@]12[H])C[C@@H](O)CC([O-])=O |
| solubility |
H2O: >10 mg/mL |
| storage temp. |
2-8°C |
| Application: |
Pravastatin sodium salt hydrate has been used in the enzymatic method to measure mevalonic acid in serum. |
| Biochem/physiol Actions: |
Competitive, water-soluble 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Inhibits cholesterol synthesis in vivo (Ki ~1 nM). |
| Biochem/physiol Actions: |
Pravastatin sodium is a competitive, water-soluble 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. |
| Features and Benefits: |
This compound was developed by Bristol-Myers Squibb . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: |
Pravastatin sodium is an orally effective hypocholesterolaemic agent which is structurally similar to lovastatin and compactin. |
| Packaging: |
25 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 2 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| mp |
171.2-173 °C |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |