6-Phosphogluconic Dehydrogenase from yeast
SIGMA/P4553 - lyophilized powder, ≥3.0 units/mg solid
Synonym: 6-Phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating); 6-Phosphogluconic Dehydrogenase from yeast
CAS Number: 9073-95-4
MDL Number: MFCD00130317
Product Type: Chemical
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| biological source | yeast |
| form | lyophilized powder |
| mol wt | 52 kDa |
| Quality Level | 200  |
| specific activity | ≥3.0 units/mg solid |
| storage temp. | 2-8°C |
| Application: | 6-Phosphogluconic Dehydrogenase from yeast has been used in hexokinase (HK) and xylose reductase (XR) activities in cell lysate. |
| Biochem/physiol Actions: | Enzyme activity is determined by measuring the reduction of NAD+ or NADP+. High levels of NADPH are believed to inhibit the enzyme, while 6-phosphogluconate acts to activate the enzyme. |
| General description: | 6-Phosphogluconic Dehydrogenase from yeast comprises of a NADP+ binding domain, α helical hydrophobic interaction domain and a C-terminal domain. It exists as dimer and the C-terminal region is crucial for the substrate binding and release. |
| Other Notes: | One unit will oxidize 1.0 μmole of 6-phospho- |
| Packaging: | 25 units in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: ≥3.0 units/mg solid |
| Storage Temp. | 2-8°C |
| Enzyme Commission (EC) Number | 1.1.1.44 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |