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PD 146176

SIGMA/P4620 - ≥98% (HPLC), solid

Synonym: 6,11-Dihydro[1]benzothiopyrano[4,3-b]indole

CAS Number: 4079-26-9
Empirical Formula (Hill Notation): C15H11NS
Molecular Weight: 237.32
MDL Number: MFCD05664738
Linear Formula: C15H11NS
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P4620-5MG 5 mg
 $222.00
1/EA		 Add To Favorites
45-P4620-25MG 25 mg
 $630.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form solid
InChI 1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2
InChI key ZGOOPZVQMLHPFM-UHFFFAOYSA-N
Quality Level 100 
SMILES string C1Sc2ccccc2-c3[nH]c4ccccc4c13
solubility DMSO: soluble >10 mg/mL
  H2O: insoluble
Application: PD 146176 has been used to study its influence on ex vivo leukotriene B4 (LTB4) and lipoxin A4 (LXA4) secretion in adipose tissue.
Biochem/physiol Actions: 15-Lipoxygenase inhibitor
Biochem/physiol Actions: PD 146176 blocks neuroprotectin D1 (NPD1) and eicosanoid synthesis by inhibiting the 5-lipoxygenase-1 (15-LOX-1) enzyme.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
UNSPSC 51111800

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