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Propafenone hydrochloride

SIGMA/P4670

Synonym: 1-[2-(2-Hydroxy-3-(propylamino)propoxy)phenyl]-3-phenyl-1-propanone hydrochloride

CAS Number: 34183-22-7
Empirical Formula (Hill Notation): C21H27NO3 · HCl
Molecular Weight: 377.90
EC Number: 251-867-9
MDL Number: MFCD00079243
Linear Formula: C21H27NO3 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P4670-5G 5 g
 $162.00
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form powder
InChI 1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H
InChI key XWIHRGFIPXWGEF-UHFFFAOYSA-N
originator Abbott
Quality Level 100 
SMILES string Cl[H].CCCNCC(O)COc1ccccc1C(=O)CCc2ccccc2
storage temp. 2-8°C
Application: Propafenone hydrochloride has been used in the isolation of cardiomyocytes.
Biochem/physiol Actions: Blocks hKv1.5 and ATP-sensitive K+ channels; class 1C antiarrhythmic agent that is also an antagonist at β adrenergic receptors.
Features and Benefits: This compound was developed by Abbott . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Propafenone hydrochloride is a calcium antagonist. It functions as a Na+ and K+ channel blocker. It might be used to treat patients with systemic hypertension. Propafenone hydrochloride is associated with bradycardia and bronchospasms. It is metabolized in the liver. Propafenone hydrochloride is used to treat ventricular arrhythmias.
Packaging: 5 g in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Storage Temp. 2-8°C
UNSPSC 41116107

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