Poly-L-glutamic acid sodium salt

SIGMA/P4761 - mol wt 15,000-50,000

Synonym: L-Glutamic acid homopolymer sodium salt

CAS Number: 26247-79-0
MDL Number: MFCD00081868
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-P4761-25MG	25 mg	$91.30 1/EA	Add To Favorites
45-P4761-100MG	100 mg	$241.00 1/EA	Add To Favorites
45-P4761-500MG	500 mg	$658.00 1/EA	Add To Favorites
45-P4761-1G	1 g	$1140.00 1/EA	Add To Favorites

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This image depicts SKU: P4761-1G

Properties
Descriptions
Safety Info.
Basic Data

application(s)	detection
color	white to off-white
form	powder
InChI	1S/C15H23N3O10/c16-7(1-4-10(19)20)13(25)17-8(2-5-11(21)22)14(26)18-9(15(27)28)3-6-12(23)24/h7-9H,1-6,16H2,(H,17,25)(H,18,26)(H,19,20)(H,21,22)(H,23,24)(H,27,28)/t7-,8-,9-/m0/s1
InChI key	BUZMZDDKFCSKOT-CIUDSAMLSA-N
mol wt	15,000-50,000
Quality Level	200
SMILES string	N([C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)[C@@H](N)CCC(=O)O
storage temp.	−20°C

Analysis Note:	Molecular weight based on viscosity.
Application:	Effect of Micelle-Incorporated Cisplatin With Sizes Ranging From 8 to 40 nm for the Therapy of Lewis Lung Carcinoma.: This research explores the use of micelle-incorporated cisplatin nanoparticles for cancer therapy, highlighting the significance of particle size on therapeutic efficacy. Poly-ʟ-glutamic acid sodium salt is used to improve drug delivery and target specificity (Wang Z et al., 2021 ). Ternary Polypeptide Nanoparticles with Improved Encapsulation, Sustained Release, and Enhanced In Vitro Efficacy of Carfilzomib.: This paper describes the development of ternary polypeptide nanoparticles, including poly-ʟ-glutamic acid sodium salt, to enhance the encapsulation and release of carfilzomib, an anticancer drug. The study demonstrates improved drug efficacy and controlled release profiles (Agbana P et al., 2020 ). Polymeric Core-Shell Nanoparticles Prepared by Spontaneous Emulsification Solvent Evaporation and Functionalized by the Layer-by-Layer Method.: This research focuses on the preparation of polymeric core-shell nanoparticles using a spontaneous emulsification method. Poly-ʟ-glutamic acid sodium salt is used to functionalize these nanoparticles, which can be applied in drug delivery systems (Szczęch M et al., 2020 ). Co-administration of Combretastatin A4 Nanoparticles and Sorafenib for Systemic Therapy of Hepatocellular Carcinoma.: This study evaluates the combined use of combretastatin A4 nanoparticles and sorafenib for treating liver cancer. Poly-ʟ-glutamic acid sodium salt is employed to enhance the stability and delivery of these nanoparticles, showing promise in improving therapeutic outcomes (Wang Y et al., 2019 ).
Other Notes:	For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource .
Packaging:	1 g in poly bottle
Packaging:	25, 100, 500 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	−20°C
UNSPSC	12352209

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