L-Phenylalanine Dehydrogenase from Sporosarcina sp.
SIGMA/P4798 - lyophilized powder, ≥6 units/mg solid
CAS Number: 69403-12-9
MDL Number: MFCD00151723
Product Type: Chemical
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| application(s) | life science and biopharma |
| biological source | bacterial (Sporosarcina sp.) |
| color | white to light brown |
| concentration | ≤100% |
| form | lyophilized powder |
| Quality Level | 200  |
| specific activity | ≥6 units/mg solid |
| storage condition | dry at room temperature |
| storage temp. | −20°C |
| Biochem/physiol Actions: | Phenylalanine dehydrogenase (PheDH) is considered an effective enzyme to estimate the quantity of phenylalanine to distinguish phenylketonuria (PKU) disease.Moreover, it is utilized for the production of optically pure l-phenylalanine, a key component of the artificial sweetener aspartame. L-Phenylalanine dehydrogenase is a NAD+-dependent oxidoreductase that catalyzes the reversible, oxidative deamination of L-phenylalanine, which results in its degradation. L-Phenylalanine dehydrogenase is used to study phenylalanine metabolism and phenylalanine, tyrosine, and tryptophan biosynthesis. |
| General description: | Research area: CELL SIGNALING Phenylalanine dehydrogenase is a member of a large family of amino-acid dehydrogenases, which includes glutamate dehydrogenase, alanine dehydrogenase, leucine dehydrogenase, lysine ε-dehydrogenase, and meso-a,ε-diaminopimelate D-dehydrogenase. The three known gene sequences are octomers. It has a two-domain, three-dimensional structure. |
| Other Notes: | One unit will oxidize 1.0 μmole of |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: ≥6 units/mg solid |
| Storage Temp. | −20°C |
| Enzyme Commission (EC) Number | 1.4.1.20 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |