Poly-L-glutamic acid sodium salt

SIGMA/P4886 - mol wt 50,000-100,000

Synonym: L-Glutamic acid homopolymer sodium salt

CAS Number: 26247-79-0
MDL Number: MFCD00081868
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-P4886-25MG	25 mg	$91.30 1/EA	Add To Favorites
45-P4886-100MG	100 mg	$228.00 1/EA	Add To Favorites
45-P4886-500MG	500 mg	$658.00 1/EA	Add To Favorites
45-P4886-1G	1 g	$1190.00 1/EA	Add To Favorites

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This image depicts SKU: P4886-100MG

12 Principles of Green Chemistry: Principle 4—Designing Safer Chemicals
Chemical products should be designed to affect their desired function while minimizing their toxicity.

12 Principles of Green Chemistry: Principle 5—Safer Solvents and Auxiliaries. This product utilizes reduced volumes of auxiliary substances that are less hazardous.

Properties
Descriptions
Safety Info.
Basic Data

application(s)	detection
color	white to off-white
form	powder
greener alternative category	, Re-engineered
greener alternative product characteristics	Designing Safer Chemicals Safer Solvents and Auxiliaries Design for Energy Efficiency Learn more about the Principles of Green Chemistry .
greener alternative product score	old score: 46 new score: 43 Find out more about DOZN™ Scoring
InChI	1S/C15H23N3O10/c16-7(1-4-10(19)20)13(25)17-8(2-5-11(21)22)14(26)18-9(15(27)28)3-6-12(23)24/h7-9H,1-6,16H2,(H,17,25)(H,18,26)(H,19,20)(H,21,22)(H,23,24)(H,27,28)/t7-,8-,9-/m0/s1
InChI key	BUZMZDDKFCSKOT-CIUDSAMLSA-N
mol wt	50,000-100,000
Quality Level	200
SMILES string	N([C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)[C@@H](N)CCC(=O)O
storage temp.	−20°C
sustainability	Greener Alternative Product

Analysis Note:	Molecular weight based on viscosity.
Application:	A real-time fluorescence assay for protease activity and inhibitor screening based on the aggregation-caused quenching of a perylene probe.: Demonstrates the utility of Poly-L-glutamic acid sodium salt in developing sensitive fluorescence assays for enzyme activity, which could streamline the development of new therapeutic inhibitors (Wang Y et al., 2018 ). Interfacial and structural characteristics of polyelectrolyte multilayers used as cushions for supported lipid bilayers.: Explores the role of Poly-L-glutamic acid sodium salt in stabilizing lipid bilayers, crucial for bio-mimetic systems and drug delivery applications (Wlodek M et al., 2017 ). The interaction of clozapine loaded nanocapsules with the hCMEC/D3 cells - In vitro model of blood brain barrier.: Highlights the use of Poly-L-glutamic acid sodium salt for drug encapsulation, enhancing the delivery of therapeutic agents across the blood-brain barrier (Łukasiewicz S et al., 2017 ). A Chimeric LysK-Lysostaphin Fusion Enzyme Lysing Staphylococcus aureus Cells: a Study of Both Kinetics of Inactivation and Specifics of Interaction with Anionic Polymers.: Investigates the synergistic effects of Poly-L-glutamic acid sodium salt in enhancing the antimicrobial properties of bio-engineered enzymes, presenting a novel approach to combat bacterial infections (Filatova LY et al., 2016 ).
General description:	We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Designing Safer Chemicals”, "Safer Solvents and Auxiliaries" and “Design for Energy Efficiency”. Click here to view its DOZN scorecard.
Other Notes:	For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource .
Packaging:	1 g in poly bottle
Packaging:	25, 100, 500 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	−20°C
UNSPSC	12352209

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