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Prostaglandin F2α tris salt

SIGMA/P5069 - synthetic, suitable for cell culture

Synonym: (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt; PGF2α−Tris

CAS Number: 38562-01-5
Empirical Formula (Hill Notation): C20H34O5 · C4H11NO3
Molecular Weight: 475.62
EC Number: 254-002-3
MDL Number: MFCD00077863
Linear Formula: C20H34O5 · C4H11NO3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P5069-1MG 1 mg
 $271.00
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assay ≥99%
biological source synthetic
form powder
InChI 1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1
InChI key IYGXEHDCSOYNKY-RZHHZEQLSA-N
Quality Level 200 
shipped in ambient
SMILES string NC(CO)(CO)CO.[H][C@]1(CC=C/CCCC(O)=O)[C@@H](O)C[C@@H](O)[C@]1([H])C=C[C@@H](O)CCCCC
solubility ethanol: 50 mg/mL, clear, colorless
storage temp. −20°C
technique(s) cell culture | mammalian: suitable
Biochem/physiol Actions: Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds.
Biochem/physiol Actions: Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. A positive feedback loop between endometrial PG F2α and luteal oxytocin is responsible for completion of luteolysis.
Biochem/physiol Actions: Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. Also stimulates contraction of smooth muscle, such as in bronchi, with possible involvement in asthma. This effect is at least partially mediated through tachykinin release.
Biochem/physiol Actions: Prostaglandin F2α is induced by uterine-produced oxytocin and acts on the corpus luteum to cause luteolysis and inhibit progesterone production.
Packaging: 1 mg in glass bottle
Purity ≥99%
Storage Temp. −20°C
UNSPSC 12352209

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