D-Pantothenic acid hemicalcium salt

SIGMA/P5155 - BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

Synonym: (R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine hemicalcium salt; Calcium D-pantothenate; Vitamin B₅

CAS Number: 137-08-6
Empirical Formula (Hill Notation): C₉H₁₆NO₅ · 0.5Ca
Molecular Weight: 238.27
EC Number: 205-278-9
MDL Number: MFCD00002766
Linear Formula: HOCH₂C(CH₃)₂CH(OH)CONHCH₂CH₂CO₂ ·1/2Ca
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-P5155-100G	100 g	$96.20 1/EA	Add To Favorites
45-P5155-500G	500 g	$389.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (TLC)
biological source	synthetic (organic)
color	white to off-white
form	powder
InChI	1S/2C9H17NO5.Ca/c21-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h27,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1
InChI key	FAPWYRCQGJNNSJ-UBKPKTQASA-L
mol wt	M_w 238.27 g/mol
pH	7.0-8 (25 °C, 50 g/L)
product line	BioReagent
Quality Level	200
SMILES string	CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO
solubility	water: soluble 50 mg/mL, clear, colorless
storage temp.	2-8°C
technique(s)	cell culture \| insect: suitable
	cell culture \| mammalian: suitable
	cell culture \| plant: suitable

Application:	D-Pantothenic acid hemicalcium salt has been used: • as a component of FMX-turbodoma- derived media • as a supplement in DMEM (Dulbecco′s modified eagle media)/F-12 used for cell proliferation • as a supplement in preadipocyte media
Application:	Precursor in the biosynthesis of coenzyme A.
Biochem/physiol Actions:	Along with coenzyme A (CoA, D-pantothenic acid is a precursor for acyl carrier protein. These are essential cofactors involved in fat, protein and carbohydrate metabolism. It also participates in the formation of acetylcholine neurotransmitter. D-pantothenic acid is considered as a source of nutrition and possesses immune function by mediating antibody formation. The production of cortisone is supported by D-pantothenic acid. It is essential for adrenal gland activity.
General description:	Due to the unstable, hygroscopic nature of the free acid, the calcium salt is employed.
General description:	Plants and microorganisms, such as Escherichia coli are the major sources of D-pantothenic acid. It is water soluble and quite stable to heating.
Packaging:	100, 500 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (TLC)
Storage Temp.	2-8°C
UNSPSC	12352205

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