Synonym: (5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,8(12),13-trien-1-oic acid; PGB2
CAS Number: 13367-85-6
Empirical Formula (Hill Notation): C20H30O4
Molecular Weight: 334.45
MDL Number: MFCD00065730
Linear Formula: C20H30O4
Product Type: Chemical
| assay |
≥98% |
| biological source |
synthetic |
| form |
solution |
| InChI |
1S/C20H30O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h4,7,12,14,17,21H,2-3,5-6,8-11,13,15H2,1H3,(H,23,24)/b7-4-,14-12+/t17-/m0/s1 |
| InChI key |
PRFXRIUZNKLRHM-HKVRTXJWSA-N |
| Quality Level |
100  |
| SMILES string |
CCCCC[C@H](O)C=CC1=C(CC=C/CCCC(O)=O)C(=O)CC1 |
| solubility |
DMSO: ~50 mg/mL |
| |
ethanol: ~100 mg/mL |
| |
PBS, pH 7.2: ~2 mg/mL |
| storage temp. |
−20°C |
| Application: |
Prostaglandin B2 has been used as an internal standard in high-performance liquid chromatography (HPLC). |
| Biochem/physiol Actions: |
Prostaglandin B2 (PGB2) is an eicosanoid and a lipid mediator. It is synthesized by the dehydration of PGE2. It is a primary prostaglandin associated with the osteoblasts and may induce pulmonary hypertension. PGB2 is also reported to inhibit glucagon stimulated glycogenolysis and forskolin-stimulated adenylate cyclase activity in plasma membranes. |
| Physical form: |
Prostaglandin B2 is supplied as a solution in methyl acetate |
| Preparation Note: |
PGB2 is provided as a solution in methyl acetate. To change the solvent, evaporate the methyl acetate under a gentle stream of nitrogen and immediately add the solvent of choice. PGB2, purged with an inert gas, is soluble in ethanol at ~100 mg/mL, DMSO at ~50 mg/mL and in dimethyl formamide at ~ 75 mg/mL. |
| Purity |
≥98% |
| Storage Temp. |
−20°C |
| UNSPSC |
12352211 |
GHS02,GHS07