Prostaglandin B2
SIGMA/P5390 - ≥98%, synthetic
Synonym: (5Z,13E,15S)
CAS Number: 13367-85-6
Empirical Formula (Hill Notation): C20H30O4
Molecular Weight: 334.45
MDL Number: MFCD00065730
Linear Formula: C20H30O4
Product Type: Chemical
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This image depicts P5390-1MG.
This image depicts P5390-1MG.
| assay | ≥98% |
| biological source | synthetic |
| form | solution |
| InChI | 1S/C20H30O4/c1-2-3-6-9-17 |
| InChI key | PRFXRIUZNKLRHM-HKVRTXJWSA |
| Quality Level | 100  |
| SMILES string | CCCCC[C@H](O)C=CC1=C(C |
| solubility | DMSO: ~50 mg/mL |
| ethanol: ~100 mg/mL | |
| PBS, pH 7.2: ~2 mg/mL | |
| storage temp. | −20°C |
| Application: | Prostaglandin B2 has been used as an internal standard in high-performance liquid chromatography (HPLC). |
| Biochem/physiol Actions: | Prostaglandin B2 (PGB2) is an eicosanoid and a lipid mediator. It is synthesized by the dehydration of PGE2. It is a primary prostaglandin associated with the osteoblasts and may induce pulmonary hypertension. PGB2 is also reported to inhibit glucagon stimulated glycogenolysis and forskolin-stimulated adenylate cyclase activity in plasma membranes. |
| Physical form: | Prostaglandin B2 is supplied as a solution in methyl acetate |
| Preparation Note: | PGB2 is provided as a solution in methyl acetate. To change the solvent, evaporate the methyl acetate under a gentle stream of nitrogen and immediately add the solvent of choice. PGB2, purged with an inert gas, is soluble in ethanol at ~100 mg/mL, DMSO at ~50 mg/mL and in dimethyl formamide at ~ 75 mg/mL. |
| Symbol |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225 - H319 - H336 |
| Precautionary statements | P210 - P305 + P351 + P338 |
| Hazard Codes | F,Xi |
| Risk Statements | 11-36-66-67 |
| Safety Statements | 9-16-26-33-36-60 |
| RIDADR | UN1231 - class 3 - PG 2 - Methyl acetate, solution |
| WGK Germany | WGK 2 |
| Flash Point(F) | 15.8 °F |
| Flash Point(C) | -9 °C |
| Supplemental Hazard Statements | EUH066 |
| Purity | ≥98% |
| Storage Temp. | −20°C |
| UNSPSC | 12352211 |