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Pyrilamine maleate salt

SIGMA/P5514

Synonym: Mepyramine maleate salt; N-(4-Methoxyphenyl)methyl-N′,N′-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine maleate salt

CAS Number: 59-33-6
Empirical Formula (Hill Notation): C17H23N3O · C4H4O4
Molecular Weight: 401.46
EC Number: 200-422-7
MDL Number: MFCD00069333
Linear Formula: C17H23N3O · C4H4O4
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-P5514-5G 5 g
$85.70
1/EA
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45-P5514-25G 25 g
$159.00
1/EA
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45-P5514-100G 100 g
$323.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P5514-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P5514-25G

 

form powder
InChI 1S/C17H23N3O.C4H4O4/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15;5-3(6)1-2-4(7)8/h4-11H,12-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key JXYWFNAQESKDNC-BTJKTKAUSA-N
originator Watson
Quality Level 100 
SMILES string OC(=O)C=C/C(O)=O.COc1ccc(CN(CCN(C)C)c2ccccn2)cc1
Application: Pyrilamine maleate salt has been used:
• to treat Cassiopea sp. as H1 receptor antagonist
• to intraperitoneally inject mice to prevent the release of endogenous histamine
• in membrane binding assay to determine the Ki values and in the comparative inhibitory concentration (IC50) studies by whole-cell patch clamp technique

Biochem/physiol Actions: Pyrilamine maleate is a H1 histamine receptor antagonist. Pyrilamine maleate induces sleep in vertebrates. In Cassiopea, it induces concentration dependent dormancy.
Features and Benefits: This compound is featured on the Histamine Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by Watson . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 5, 25, 100 g in glass bottle
UNSPSC 12352116

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