Poloxamer 188 solution
SIGMA/P5556 - 10%, sterile-filtered, BioReagent, suitable for insect cell culture
Synonym: Nonionic copolymer surfactant
CAS Number: 9003-11-6
MDL Number: MFCD00082049
Product Type: Chemical
| concentration | 10% |
| description | non-ionic |
| HLB | 29 |
| impurities | endotoxin, tested |
| InChI | 1S/C3H6O.C2H4O/c1-3-2-4-3 |
| InChI key | RVGRUAULSDPKGF-UHFFFAOYSA |
| mol wt | average mol wt 8350 |
| product line | BioReagent |
| Quality Level | 400 ![]() |
| SMILES string | O2C(C2)C.O1CC1 |
| sterility | sterile-filtered |
| technique(s) | cell culture | insect: suitable |
| transition temp | cloud point ≥100 |
| Application: | A nonionic copolymer surfactant |
| Biochem/physiol Actions: | Poloxamer 188 (P188) elicits hemorheological, antithrombotic, anti-inflammatory, and cytoprotective activities. It restores and stabilizes membrane barrier function. P188 also inhibits lipid peroxidation, reduces surface tension and hydrophobic-based cellular adherence. P-188 exhibits low toxicity and may be used in oral drug delivery. |
| General description: | Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer. It comprises a central chain of hydrophobic polyoxypropyl |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12161902 |

