Palmitic acid
SIGMA/P5585 - BioXtra, ≥99%
Synonym: 1-
CAS Number: 57-10-3
Empirical Formula (Hill Notation): C16H32O2
Molecular Weight: 256.42
EC Number: 200-312-9
MDL Number: MFCD00002747
Linear Formula: CH3(CH2)14COOH
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: P5585-100G
This image depicts SKU: P5585-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: P5585-25G
This image depicts SKU: P5585-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: P5585-10G
This image depicts SKU: P5585-10G
| anion traces | chloride (Cl-): ≤0.05% |
| sulfate (SO42-): ≤0.05% | |
| assay | ≥99% |
| biological source | plant (vegetable) |
| bp | 271.5 °C/100 mmHg (lit.) |
| cation traces | Al: ≤0.005% |
| Ca: ≤0.0005% | |
| Cu: ≤0.0005% | |
| Fe: ≤0.0005% | |
| K: ≤0.005% | |
| Mg: ≤0.0005% | |
| Na: ≤0.05% | |
| NH4+: ≤0.05% | |
| Pb: ≤0.001% | |
| Zn: ≤0.0005% | |
| density | 0.852 g/mL at 25 °C (lit.) |
| form | powder |
| functional group | carboxylic acid |
| grade | BioPerformance Certified |
| ign. residue | ≤0.1% |
| impurities | ≤0.0005% Phosphorus (P) |
| ≤0.1% Insoluble matter | |
| InChI | 1S/C16H32O2/c1-2-3-4-5-6- |
| InChI key | IPCSVZSSVZVIGE-UHFFFAOYSA |
| lipid type | saturated FAs |
| mp | 61-62.5 °C (lit.) |
| product line | BioXtra |
| Quality Level | 200  |
| shipped in | ambient |
| SMILES string | CCCCCCCCCCCCCCCC(O)=O |
| solubility | chloroform: 0.5 M, clear, colorless |
| storage temp. | room temp |
| technique(s) | cell culture | mammalian: suitable |
| vapor pressure | 10 mmHg ( 210 °C) |
| Application: | Palmitic acid has been used: • as a medium supplement in chorionic villous tissue culture form placenta • as a component of hormone pellet for implantation in mice ovary • for inducing expression of immunity-related GTPase M (IRGM) in human monocytic cell line, THP-1 |
| Biochem/physiol Actions: | Palmitic acid (PA) is a component of membrane phospholipids (PL) and adipose triacylglycerols (TAG). Elevated levels of palmitic acid contributes to the pathophysiology of atherosclerosis, type 2 diabetes mellitus, neurodegenerative diseases, obesity and cancer. PA promotes apoptosis in the endothelial cell by modulating the p38 mitogen-activated protein kinase (MAPK) pathway and favors expression of TNF-α and reactive oxygen species accumulation. PA promotes interleukin 8 (IL-8) synthesis in hepatocytes contributing to hepatic inflammation. PA by interacting with toll-like receptor 4 (TLR4) induces inflammatory injury in cardiomyoctes. |
| Biochem/physiol Actions: | Palmitic acid is a straight-chain 16-carbon fatty acid. Diets rich in palmitic acid, along with lauric and myristic acids, are associated with increased serum levels of low-density lipoprotein cholesterol. Palmitic acid is the first fatty acid produced by lipogenesis. It is a negative regulator of acetyl-CoA carboxylase (ACC) and is implicated in fatty acid-induced insulin resistance. |
| Packaging: | 10, 25, 100 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | 235.4 °F |
| Flash Point(C) | 113 °C |
| Purity | ≥99% |
| bp | 271.5 °C/100 mmHg (lit.) |
| mp | 61-62.5 °C (lit.) |
| Density | 0.852 g/mL at 25 °C (lit.) |
| Storage Temp. | room temp |
| UNSPSC | 12352106 |