Pasteurella multocida toxin
SIGMA/P5806 - lyophilized powder
Synonym: PMT
CAS Number: 129876-91-1
MDL Number: MFCD00131803
Product Type: Chemical
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| form | lyophilized powder |
| packaging | vial of 50 μg toxin (Also contains 10 mM Tris, 0.1 M NaCl, and 0.1% sucrose, pH 8.3.) |
| Quality Level | 200  |
| sterility | sterile-filtered |
| storage temp. | −20°C |
| Biochem/physiol Actions: | Pasteurella multocida toxin (PMT) is a bacterial protein toxin produced by few P. multocida serotype A and D strains. It acts as an effective mitogen in numerous cell types in vitro. PMT inhibits osteoblast differentiation by activating the Rho/Rho-associated coiled-coil containing protein kinase (Rho/ROCK) pathway. Infections of PMT cause atrophic rhinitis in pigs and by local dermatonecrosis, respiratory disease in cattle and rabbits. PMT is also a pathogenic agent of dermatonecrosis and bacteremia in humans. |
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| Features and Benefits: | This compound is featured on the G Proteins (Heterotrimeric) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| RIDADR | UN 3462 6.1 / PGI |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |