p-Phenylenediamine
SIGMA/P6001 - 98% (GC)
Synonym: 1,4-Benzenediamine; 1,4-Diaminobenzene; 1,4-Phenylenediamine
CAS Number: 106-50-3
Empirical Formula (Hill Notation): C6H8N2
Molecular Weight: 108.14
EC Number: 203-404-7
MDL Number: MFCD00007901
Linear Formula: C6H4(NH2)2
Product Type: Chemical
| assay | 98% (GC) |
| bp | 267 °C (lit.) |
| description | anti-fade reagent |
| InChI | 1S/C6H8N2/c7-5-1-2-6(8)4- |
| InChI key | CBCKQZAAMUWICA-UHFFFAOYSA |
| mp | 138-143 °C (lit.) |
| Quality Level | 200 ![]() |
| SMILES string | Nc1ccc(N)cc1 |
| vapor density | 3.7 (vs air) |
| vapor pressure | 1.08 mmHg ( 100 °C) |
| Application: | p-Phenylenediamine has been used: • to evaluate its sensitization potential in vitro in langerhans-like dendritic cells and autologous T cells • to treat the dorsal sides of the ears of mice, to study its systemic immunological effects • in glycerol to coverslip coronal sections in the attempt to count Aβ plaques Anti-fade reagent is added to the mounting medium in fluorescence microscopy to retard photobleaching of fluorescein and other fluorescent dyes. |
| Biochem/physiol Actions: | p-Phenylenediamine causes allergic reactions with skin. It is widely used in hair dyes. It eventually forms Bandrowski′s base, which is found to be the primary cause for allergy. p-Phenylenediamine exposure results in dermatitis, urticaria and anaphylaxis. It acts as an electron donor and is known to reduce cytochrome c. |
| Disclaimer: | Darkens in storage. |
| Packaging: | 1 kg in glass bottle |
| Packaging: | 50, 100, 250 g in glass bottle |
| Symbol | ![]() ![]() GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H301 + H311 + H331 - H317 - H319 - H370 - H410 |
| Precautionary statements | P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338 |
| Hazard Codes | T,N |
| Risk Statements | 23/24/25-36-43-48/22-50/53 |
| Safety Statements | 28-36/37-45-60-61 |
| RIDADR | UN 1673 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 230.0 °F - closed cup |
| Flash Point(C) | 110 °C - closed cup |
| Purity | 98% (GC) |
| bp | 267 °C (lit.) |
| mp | 138-143 °C (lit.) |
| UNSPSC | 12352204 |




