Synonym: 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione; 1-Dehydrocortisol; 1-Dehydrohydrocortisone; 11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione
CAS Number: 50-24-8
Empirical Formula (Hill Notation): C21H28O5
Molecular Weight: 360.44
EC Number: 200-021-7
MDL Number: MFCD00003649
Linear Formula: C21H28O5
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P6004-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P6004-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P6004-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P6004-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P6004-10G
| assay |
≥99% |
| biological source |
synthetic (organic) |
| form |
powder |
| InChI |
1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 |
| InChI key |
OIGNJSKKLXVSLS-VWUMJDOOSA-N |
| mp |
240 °C (dec.) (lit.) |
| originator |
Johnson & Johnson |
| Quality Level |
200  |
| shipped in |
ambient |
| SMILES string |
O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(CO)=O)=C1 |
| solubility |
chloroform: methanol (1:1): 50 mg/mL, clear, colorless to faintly yellow |
| sterility |
non-sterile |
| storage temp. |
room temp |
| Analysis Note: |
Actual content given on label |
| Application: |
Prednisolone has been used for the Δ1-dehydrogenation of hydrocortisone by gel entrapped arthrobacter simplex cells. |
| Biochem/physiol Actions: |
Prednisolone is a glucocorticoid with anti-inflammatory and immunosuppressive activity. |
| Features and Benefits: |
This compound was developed by Johnson & Johnson . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: |
Prednisolone prevents protease activity in vitro. It stimulates myogenesis and inhibits apoptosis. Prednisolone is used to treat Duchenne muscular dystrophy (DMD), gout arthritis and chronic obstructive pulmonary disease (COPD) exacerbations. |
| Packaging: |
1, 5, 10, 25 g in poly bottle |
| Packaging: |
100 mg in poly bottle |
| Purity |
≥99% |
| mp |
240 °C (dec.) (lit.) |
| Storage Temp. |
room temp |
| UNSPSC |
12352200 |