(R)-(−)-Phenylephrine hydrochloride
SIGMA/P6126 - powder
Synonym: (R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride; (R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride
CAS Number: 61-76-7
Empirical Formula (Hill Notation): C9H13NO2 · HCl
Molecular Weight: 203.67
EC Number: 200-517-3
MDL Number: MFCD00012605
Linear Formula: HOC6H4CH(CH2NHCH3)OH·HCl
Product Type: Chemical
| form | powder |
| InChI | 1S/C9H13NO2.ClH/c1-10-6-9 |
| InChI key | OCYSGIYOVXAGKQ-FVGYRXGTSA |
| mp | 143-145 °C (lit.) |
| originator | Johnson & Johnson |
| Quality Level | 200 ![]() |
| SMILES string | OC1=CC([C@H](CNC)O)=CC=C1 |
| Application: | (R)-(-)-Phenylephrine hydrochloride has been used: • in the preparation and culturing of cardiocytes and fibroblasts • to stimulate myocardial strips to measure slice contraction • in primary cardiomyocyte culture to show the effect of Kruppel-like factors (KLF) on cardiac hypertrophy in vivo • to evaluate the pharmacological response of embryonic stem cell (ESC)-derived cardiomyocytes • to pharmacologically rescue GATA (erythroid transcription factor) binding protein 3 (GATA3) null embryo from early embryonic lethality |
| Biochem/physiol Actions: | α1-adrenoceptor agonist. |
| Features and Benefits: | This compound is featured on the α1-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by Johnson & Johnson . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: | (R)-(-)-Phenylephrine hydrochloride is an adrenergic agent, which functions as a β-receptor sympathomimetic drug. |
| Packaging: | 5, 10, 25, 50, 100 g in glass bottle |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H302 - H317 |
| Precautionary statements | P261 - P264 - P270 - P280 - P301 + P312 - P302 + P352 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 143-145 °C (lit.) |
| UNSPSC | 12352200 |


