Prednisone

SIGMA/P6254 - ≥98%

Synonym: 1,4-Pregnadiene-17α,21-diol-3,11,20-trione; 1-Cortisone; 17α,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione; Dehydrocortisone

CAS Number: 53-03-2
Empirical Formula (Hill Notation): C₂₁H₂₆O₅
Molecular Weight: 358.43
EC Number: 200-160-3
MDL Number: MFCD00003608
Linear Formula: C₂₁H₂₆O₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-P6254-1G	1 g	$48.60 1/EA	Add To Favorites
45-P6254-5G	5 g	$178.00 1/EA	Add To Favorites
45-P6254-10G	10 g	$315.00 1/EA	Add To Favorites
45-P6254-25G	25 g	$607.00 1/EA	Add To Favorites

FT-IR Spectra for 1,4-Pregnadiene-17α,21-diol-3,11,20-trione.

Properties
Descriptions
Safety Info.
Basic Data

application(s)	hematology
assay	≥98%
biological source	synthetic
form	powder
InChI	1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
InChI key	XOFYZVNMUHMLCC-ZPOLXVRWSA-N
mp	236-238 °C (lit.)
Quality Level	200
shipped in	ambient
SMILES string	O=C1C=C[C@@]2(C)C(CC[C@]([C@@](CC[C@@]3(C(CO)=O)O)([H])[C@]3(C)C4)([H])[C@]2([H])C4=O)=C1
solubility	chloroform/ethanol (1:1): 50 mg/mL, clear, colorless to light yellow
sterility	non-sterile
storage temp.	room temp

Application:	Prednisone has been used in dimethyl sulfoxide stock suspension to inject into experimental mice and to analyze the effects of glucocorticoid steroid. It has also been used as a test drug, formulated with peanut butter to study the effects of daily administration of MIDD0301, by animal weight, organ weight and haematological analysis.
Biochem/physiol Actions:	Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activity. It is useful in treating many disease states and has a half-life of 3.4 to 3.8 hours in plasma. Prednisone is metabolized to prednisolone, which is physiologically active.
Features and Benefits:	This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	1 g in poly tube
Packaging:	5, 10, 25 g in poly bottle

Symbol	GHS08
Signal word	Warning
Hazard statements	H373
Precautionary statements	P260
Hazard Codes	Xn
Risk Statements	63
Safety Statements	36/37/39-45
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98%
mp	236-238 °C (lit.)
Storage Temp.	room temp
UNSPSC	12352200

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