Anti-Purinergic Receptor P2Y1 antibody produced in rabbit
SIGMA/P6487 - affinity isolated antibody, lyophilized powder
Product Type: Chemical
Immunohistochemistry Anti-P2Y1 Receptor: Cat. No. P6487: Immunohistochemical staining of Fasciculi in Rat thalamus using Anti-P2Y1 Receptor antibody. Specific staining is black. Cresyl violet is used as the counterstain.
Immunoblotting Anti-P2Y1 Receptor: Cat. No. P6487: Western blot analysis of Rat brain membranes (lanes 1,3) and human platelets lysate (lanes 2,4). Lanes 1,2. Anti-P2Y1 Receptor antibody, (1:200). 3,4. Anti-P2Y1 Receptor antibody, preincubated with the control peptide antigen.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | lyophilized powder |
| Quality Level | 100  |
| species reactivity | human, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P47900  |
| Application: | Anti-Purinergic Receptor P2Y1 antibody produced in rabbit has been used in western blotting1:200 and immunohistochemistry at a dilution of 1:50. |
| Biochem/physiol Actions: | Purinergic Receptor P2Y1 acts as a receptor for extracellular ATP and ADP. It is essential for ADP-induced platelet activation, aggregation, and thrombosis. P2Y1 also participates in endothelial cell-based nucleotide-induced relaxation and in calcium mobilization. It serves as a potential target for the generation of new antiplatelet compounds and anti-inflammatory strategies. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Purinergic Receptor P2Y1 is a member of G protein-coupled receptors. The P2Y1 gene is mapped to human chromosome 3q25.2. It is present in the heart, blood vessels, prostate, testis, ovary, and neural tissue. |
| Immunogen: | synthetic peptide corresponding to residues 242-258 of rat or human P2Y1. |
| Physical form: | Lyophilized from phosphate buffered saline, pH 7.4, 1% bovine serum albumin and 0.05% sodium azide. |
| Hazard statements | H412 |
| Precautionary statements | P273 |
| Hazard Codes | Xn |
| Risk Statements | 21/22-52/53 |
| Safety Statements | 36/37-61 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |