Pilocarpine nitrate salt

SIGMA/P6628 - ≥98% (HPLC)

CAS Number: 148-72-1
Empirical Formula (Hill Notation): C₁₁H₁₆N₂O₂ · HNO₃
Molecular Weight: 271.27
EC Number: 205-723-7
MDL Number: MFCD00078497
Linear Formula: C₁₁H₁₆N₂O₂ · HNO₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-P6628-10G	10 g	$269.00 1/EA		Add To Favorites
45-P6628-25G	25 g	$566.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white
form	powder
InChI	1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1
InChI key	PRZXEPJJHQYOGF-GNAZCLTHSA-N
optical activity	[α]25/D +83°, c = 10 in H₂O(lit.)
Quality Level	100
SMILES string	O[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C
solubility	H₂O: 100 mg/mL

Application:	Pilocarpine nitrate salt has been used to measure bronchoconstriction and M2 and M3 muscarinic receptor function in vivo. It has also been used to induce electrographic and behavioral seizures and to study the different patterns of neuronal activation and neurodegeneration in Proechimys rats and Wistar rats.
Biochem/physiol Actions:	Nonselective muscarinic acetylcholine receptor agonist.
Biochem/physiol Actions:	Nonselective muscarinic acetylcholine receptor agonist; used to produce an experimental model of epilepsy.
Biochem/physiol Actions:	Pilocarpine is a cholinergic muscarinic agonist, useful in inducing epilepsy in animal models. It is specially used to study the pathogenesis of epileptogenesis and pharmacoresistant epilepsy. Pilocarpine application is more popular among the rat and mice models.

Symbol	GHS03,GHS06
Signal word	Danger
Hazard statements	H272 - H302 - H330
Precautionary statements	P210 - P220 - P260 - P264 - P301 + P312 - P304 + P340 + P310
Hazard Codes	T+
Risk Statements	26/28
Safety Statements	25-45
RIDADR	UN 2811 6.1 / PGII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
UNSPSC	12352200

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