Picric acid solution
SIGMA/P6744 - 1.3% in H2O (saturated)
Synonym: 2,4,6-Trinitrophenol
CAS Number: 88-89-1
Empirical Formula (Hill Notation): C6H3N3O7
Molecular Weight: 229.10
MDL Number: MFCD00007102
Linear Formula: (O2N)3C6H2OH
Product Type: Chemical
| application(s) | hematology histology |
| color | yellow to very dark yellow |
| concentration | 1.3% in H2O (saturated) |
| density | 1.080 g/cm3 |
| form | liquid |
| InChI | 1S/C6H3N3O7/c10-6-4(8(13) |
| InChI key | OXNIZHLAWKMVMX-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | Oc1c(cc(cc1[N+]([O-])=O)[ |
| storage temp. | room temp |
| Application: | Picric acid is commonly used as a fixative and staining reagent in forensic and histological applications. It is a general cytoplasmic stain, connective tissue fiber stain, and a fixative for tissues.• It is a component of picrosirius red which is used to stain collagen. • Bouin’s fluid which also comprises picric acid is a fixative for nuclei and connective tissue. • It can be used as a colorimetric reagent in creatinine determination assay. |
| General description: | Picric acid is a polynitrated aromatic acid. It dissolves in water to form a solution with low pH (pH 2.0). It interacts with basic groups of proteins, forms salts and coagulates them. Fixation with picric acid gives a bright stain, but there might be a loss of nucleic acids due to the low pH of the solution. Picric acid is anionic and has a low molecular weight. |
| Packaging: | 1 gal in poly bottle |
| Risk Statements | 1 |
| Safety Statements | 35 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Supplemental Hazard Statements | EUH001 |
| Density | 1.080 g/cm3 |
| Storage Temp. | room temp |
| UNSPSC | 12171500 |