Prostaglandin A₁

SIGMA/P7265 - synthetic

Synonym: (13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid; PGA₁

CAS Number: 14152-28-4
Empirical Formula (Hill Notation): C₂₀H₃₂O₄
Molecular Weight: 336.47
MDL Number: MFCD00077858
Linear Formula: C₂₀H₃₂O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-P7265-1MG	1 mg	$178.00 1/EA		Add To Favorites
45-P7265-5MG	5 mg	$616.00 1/EA		Add To Favorites
45-P7265-10MG	10 mg	$1040.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98%
biological source	synthetic
form	powder
InChI	1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12-18,21H,2-11H2,1H3,(H,23,24)/b14-12+/t16-,17-,18+/m0/s1
InChI key	BGKHCLZFGPIKKU-LDDQNKHRSA-N
Quality Level	200
SMILES string	O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)C=C1
storage temp.	−20°C

Biochem/physiol Actions:	Prostaglandin A1 (PGA1) is a cyclopentenone prostaglandin containing chemically reactive α,β-unsaturated carbonyl. This cyclooxygenase 2 (COX-2) metabolic product aids in regulating the development and progression of Alzheimer′s disease (AD). In addition, PGA1 also regulates various biological processes via Michael addition. It exhibits antiviral activity against avian influenza A viruses (IAV) by inducing cytoprotective heat shock response in infected cells and by inhibiting nuclear factor-κB (NF-κB) activity.
Packaging:	10 mg in poly bottle
Packaging:	5 mg in glass bottle

Symbol	GHS07,GHS08
Signal word	Danger
Hazard statements	H302 - H360F
Precautionary statements	P201 - P301 + P312 + P330 - P308 + P313
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98%
Storage Temp.	−20°C
UNSPSC	12352211

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