PAK7 Active human
SIGMA/P7373 - ≥75% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution
Synonym: PAK5; p21 activated kinase-7
MDL Number: MFCD07371026
Product Type: Chemical
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
| assay | ≥75% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | protein apparent mol wt ~116 kDa by SDS-PAGE |
| Quality Level | 200  |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| specific activity | 10 units/mg protein (Bradford) |
| storage temp. | −70°C |
| UniProt accession no. | Q9P286  |
| Biochem/physiol Actions: | PAK7 is a PAK family kinase that contains a CDC42/Rac1 interactive binding (CRIB) motif at the N-terminus and a Ste20-like kinase domain at the C-terminus. PAK7 has been implicated in the regulation of cell morphology, motility and transformation. PAK7 is moderately expressed in adult and fetal whole brain and in all specific adult brain regions tested. |
| Other Notes: | One unit will incorporate one nanomole of phosphate into the peptide substrate CKRPRAASFAE per minute at 30 °C and pH 7.2 using a final concentration of 50 μM [32P] ATP. |
| Physical form: | Solution in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥75% (SDS-PAGE) |
| activity | specific activity: 10 units/mg protein (Bradford) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |