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Pirenzepine dihydrochloride

SIGMA/P7412 - ≥98% (TLC), powder

Synonym: 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride

CAS Number: 29868-97-1
Empirical Formula (Hill Notation): C19H21N5O2 · 2HCl
Molecular Weight: 424.32
EC Number: 249-907-5
MDL Number: MFCD00055214
Linear Formula: C19H21N5O2 · 2HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P7412-500MG 500 mg
 $124.00
1/EA		 Add To Favorites
45-P7412-1G 1 g
 $221.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P7412-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P7412-500MG

 

assay ≥98% (TLC)
color white to light yellow
form powder
InChI 1S/C19H21N5O2.2ClH/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24;;/h2-8H,9-13H2,1H3,(H,21,26);2*1H
InChI key FFNMBRCFFADNAO-UHFFFAOYSA-N
Quality Level 200 
SMILES string Cl[H].Cl[H].CN1CCN(CC1)CC(=O)N2c3ccccc3C(=O)Nc4cccnc24
solubility H2O: 50 mg/mL
Application: Pirenzepine dihydrochloride has been used
• in transactivation of fibroblast growth factor receptor (FGFR).
• as a supplement in cell culture.
• for the stimulation of human fibroblasts
Biochem/physiol Actions: Selective M1 muscarinic acetylcholine receptor antagonist.
Disclaimer: Hygroscopic; store desiccated at room temperature.
Features and Benefits: This compound is a featured product for Neuroscience research. Click here  to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the Acetylcholine Receptors (Muscarinic)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description: Pirenzepine dihydrochloride is an anticholinergic agent. It is also considered as an antiulcer drug. It is used to treat myopia, gastric and duodenal ulcers. Pirenzepine dihydrochloride induces the dimerization of muscarinic M1 receptors.
Packaging: 1 g in poly bottle
Packaging: 500 mg in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (TLC)
UNSPSC 12352200

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