Putrescine dihydrochloride
SIGMA/P7505 - ≥98% (TLC)
Synonym: 1,4-Butanediamine dihydrochloride; 1,4-Diaminobutane dihydrochloride; Tetramethylenediamine dihydrochloride
CAS Number: 333-93-7
Empirical Formula (Hill Notation): C4H12N2 · 2HCl
Molecular Weight: 161.07
EC Number: 206-375-9
MDL Number: MFCD00012526
Linear Formula: NH2(CH2)4NH2 · 2HCl
Product Type: Chemical
| assay | ≥98% (TLC) |
| form | powder |
| InChI | 1S/C4H12N2.2ClH/c5-3-1-2- |
| InChI key | XXWCODXIQWIHQN-UHFFFAOYSA |
| mp | 280 °C (dec.) (lit.) |
| Quality Level | 400 ![]() |
| SMILES string | Cl[H].Cl[H].NCCCCN |
| solubility | H2O: soluble 100 mg/mL, clear, colorless |
| Application: | Putrescine dihydrochloride has been used: • as a bioactive amine standard in high-performance liquid chromatography (HPLC) • as a component of hormone mix supplemented to Dulbecco′s modified eagle medium (DMEM) to study its effects on neural stem cells • as a supplement in DMEM for culturing of endometrial cancer cells |
| Biochem/physiol Actions: | Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine. |
| Biochem/physiol Actions: | Binds to the polyamine modulatory site of the NMDA receptor; potentiates NMDA-induced currents. |
| Biochem/physiol Actions: | Putrescine is an aliphatic amine and is positively charged. It acts as a precursor of spermine and plays a role in polyamine biosynthesis. Putrescine is found in several plants, animals, and bacteria. It plays a role in cell proliferation and cell growth in Escherichia coli. Putrescine is a component of agrochemicals, surfactants, pharmaceuticals, polymers, and additives. |
| Symbol | ![]() GHS05,GHS06 |
| Signal word | Danger |
| Hazard statements | H302 - H311 - H314 - H330 |
| Precautionary statements | P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Purity | ≥98% (TLC) |
| mp | 280 °C (dec.) (lit.) |
| UNSPSC | 12352200 |



