Prostaglandin E1
SIGMA/P7527 - powder, γ-irradiated, BioXtra, suitable for cell culture
Synonym: (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid; Alprostadil; PGE1
CAS Number: 745-65-3
Empirical Formula (Hill Notation): C20H34O5
Molecular Weight: 354.48
EC Number: 212-017-2
MDL Number: MFCD00077860
Linear Formula: C20H34O5
Product Type: Chemical
| assay | ≥60% (HPLC) |
| biological source | synthetic (organic) |
| concentration | ≥60% (HPLC) |
| form | powder |
| InChI | 1S/C20H34O5/c1-2-3-6-9-15 |
| InChI key | GMVPRGQOIOIIMI-DWKJAMRDSA |
| product line | BioXtra |
| Quality Level | 200  |
| SMILES string | O=C1[C@H](CCCCCCC(O)=O)[C |
| solubility | ethanol: 1 mg/mL |
| sterility | γ-irradiated |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| Application: | For use in cell culture applications for the study of prostaglandin regulated cell signaling and gene regulation. |
| Application: | Prostaglandin E1 has been used in maintaining mice proximal tubule, and NRK-52E, a rat renal epithelial cell line. |
| Biochem/physiol Actions: | Prostaglandins mediate vasodilation and vasoconstriction, the E series of prostaglandin is a highly effective vasodilator. It is known to efficiently cause erythema. Prostaglandin E1 is considered as a potent pyretic factor, and acts through cerebral ventricles. Prostaglandin E1 is useful to prolong cardiovascular function in new born suffering from ductus-dependant congenital heart disease until surgery. |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 + P330 |
| Hazard Codes | Xn |
| Risk Statements | 61-22 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥60% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352209 |