Progesterone-Water Soluble

SIGMA/P7556 - powder, BioReagent, suitable for cell culture

Synonym: Progesterone: HBC complex; Progesterone: methyl-β-cyclodextrin complex

MDL Number: MFCD00003658
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-P7556-100MG	100 mg	$289.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥65% (HPLC)
biological source	synthetic (organic)
concentration	≥65% (HPLC)
form	powder
InChI	1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
InChI key	RJKFOVLPORLFTN-LEKSSAKUSA-N
product line	BioReagent
Quality Level	200
shipped in	ambient
SMILES string	[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])C(C)=O
solubility	H₂O: 25 mg/mL, clear to slightly hazy
storage temp.	room temp
technique(s)	cell culture \| mammalian: suitable

Application:	Progesterone-Water Soluble has been used: • for in vitro maturation of oocyte complexes • as a σ1R antagonist to study its effect on sigma 1 receptor • to study its effect on the differentiation of human multipotent mesenchymal stromal cells (hMSCs) in vitro
Application:	This product is not recommended for use in binding assays.
Biochem/physiol Actions:	Progesterone is a hormone that maintains pregnancy. It is essential for embryo formation, development and survival in almost all mammals. This hormone exhibits its action via progesterone receptor, which is specifically expressed in the endometrial stroma throughout pregnancy. It is known to prevent preterm delivery, when administered intramuscularly. Progesterone also controls gonadotropin secretion, activates sexual behavior and triggers ovarian events leading to ovulation. It stimulates the growth and differentiation of the uterus and prevents uterine contractility.
General description:	Progesterone is a steroid hormone secreted by the ovaries.
Other Notes:	Contains approx. 70 mg progesterone per gram; balance methyl-β-cyclodextrin.
Packaging:	100 mg in glass bottle
Packaging:	Package size based on progesterone content

Symbol	GHS08
Signal word	Danger
Hazard statements	H351 - H360FD - H362
Precautionary statements	P202 - P260 - P263 - P264 - P270 - P308 + P313
Hazard Codes	Xn
Risk Statements	40-62
Safety Statements	36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥65% (HPLC)
Storage Temp.	room temp
UNSPSC	12352209

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