Synonym: 1,4-Piperazinediethanesulfonic acid dipotassium salt; Piperazine-1,4-bis(2-ethanesulfonic acid) dipotassium salt
CAS Number: 108321-27-3
Empirical Formula (Hill Notation): C8H16K2N2O6S2
Molecular Weight: 378.55
MDL Number: MFCD00069751
Linear Formula: C8H16K2N2O6S2
Product Type: Chemical
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This image depicts SKU: P7643-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: P7643-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: P7643-500G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: P7643-1KG
| application(s) |
diagnostic assay manufacturing |
| assay |
≥99% (titration) |
| form |
crystalline powder |
| InChI |
1S/C8H18N2O6S2.2K/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16;;/h1-8H2,(H,11,12,13)(H,14,15,16);;/q;2*+1/p-2 |
| InChI key |
BJQYFCAMUXGZFN-UHFFFAOYSA-L |
| pKa (25 °C) |
6.8 |
| Quality Level |
200  |
| SMILES string |
[K+].[K+].[O-]S(=O)(=O)CCN1CCN(CC1)CCS([O-])(=O)=O |
| solubility |
water: 0.25 g/mL, clear, colorless |
| useful pH range |
6.1-7.5 |
| Application: |
PIPES (1,4-Piperazinediethanesulfonic acid) dipotassium salt has been used as buffer for fluorescence polarization microscopy studies of kinesin-microtubule binding. It is suitable for use as a component of PHEM buffer ([K-PIPES], HEPES, EGTA, and MgSO4) used during rinsing and blocking steps in immunofluorescence imaging of HeLa cells. It is also suitable for use as buffer for purification of tubulin. |
| General description: |
PIPES (1,4-Piperazinediethanesulfonic acid) is a zwitterionic buffer. It is a stable buffer and is used majorly in fixation solutions. PIPES is inert towards enzymatic and non-enzymatic reactions. However, it generates artefacts in transmission electron microscope imaging. |
| Packaging: |
1 kg in poly bottle |
| Packaging: |
25, 100, 500 g in poly bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥99% (titration) |
| UNSPSC |
12161700 |