Pargyline hydrochloride
SIGMA/P8013
Synonym: N-Methyl-N-
CAS Number: 306-07-0
Empirical Formula (Hill Notation): C11H13N · HCl
Molecular Weight: 195.69
EC Number: 206-175-1
MDL Number: MFCD00012492
Linear Formula: C6H5CH2N(CH3)CH2C≡CH·HCl
Product Type: Chemical
| assay | 98% (TLC) |
| biological source | synthetic |
| form | powder or crystals |
| InChI | 1S/C11H13N.ClH/c1-3-9-12( |
| InChI key | BCXCABRDBBWWGY-UHFFFAOYSA |
| mp | 160-163 °C (lit.) |
| Quality Level | 200  |
| SMILES string | Cl[H].CN(CC#C)Cc1ccccc1 |
| solubility | water: 50 mg/mL, clear, colorless to faintly yellow |
| storage temp. | −20°C |
| Application: | Pargyline hydrochloride has been used: • as a histone demethylase inhibitor to treat monocytes to investigate whether various inhibitors affect training • to maximize uptake into dopaminergic neurons (DA) neurons in experimental rats, • to study its effect on discolouration of medullary tissues of sclerotia of S. sclerotiorum |
| Biochem/physiol Actions: | Pargyline hydrochloride acts as a histone demethylase inhibitor. It has antihypertensive action. |
| Biochem/physiol Actions: | Selective MAO-B inhibitor. |
| Packaging: | 1, 5 g in glass bottle |
| Packaging: | 500 mg in glass bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 22-24/25 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 98% (TLC) |
| mp | 160-163 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |