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Picrotoxinin

SIGMA/P8390

CAS Number: 17617-45-7
Empirical Formula (Hill Notation): C15H16O6
Molecular Weight: 292.28
MDL Number: MFCD00078765
Linear Formula: C15H16O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P8390-250MG 250 mg
 $265.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P8390-250MG

 

form powder
InChI 1S/C15H16O6/c1-5(2)7-8-11(16)19-9(7)10-13(3)14(8,18)4-6-15(13,21-6)12(17)20-10/h6-10,18H,1,4H2,2-3H3/t6-,7+,8+,9-,10-,13-,14-,15+/m1/s1
InChI key PIMZUZSSNYHVCU-KBLUICEQSA-N
Quality Level 200 
SMILES string [H][C@@]12OC(=O)[C@]([H])([C@@H]1C(C)=C)[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@@]2([H])[C@]35C
Application: Picrotoxinin has been used as an agonist of taste 2 receptor member 14 (TAS2R14) to perform an array-based bitter receptor screening assay and to study the effect of calcium buffering and calcium sensor type on its sensitivity.
Biochem/physiol Actions: GABAA receptor antagonist; binds to the GABA receptor-linked Cl− channel.
Biochem/physiol Actions: Picrotoxinin acts as a potent convulsant.
Features and Benefits: This compound is a featured product for Neuroscience research. Click here  to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the Glycine Receptor  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description: Picrotoxinin is a component of picrotoxin and can be derived from plants. It is a non-nitrogenous compound.
Other Notes: Active component of picrotoxin
Packaging: 250 mg in glass bottle
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H300
Precautionary statements P301 + P310 + P330
Hazard Codes T+
Risk Statements 28
Safety Statements 28-36/37-45
RIDADR UN 2811 6.1 / PGII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 41116107

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