Paromomycin sulfate salt
SIGMA/P8692 - suitable for plant cell culture, BioReagent
CAS Number: 1263-89-4
Empirical Formula (Hill Notation): C23H45N5O14 · xH2SO4
Molecular Weight: 615.63 (free base basis)
Linear Formula: C23H45N5O14 · xH2SO4
Product Type: Chemical
| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| application(s) | agriculture |
| form | powder |
| InChI | 1S/C23H45N5O14.CH4/c24-2- |
| InChI key | OYJABWUHUYVDMJ-UDXJMMFXSA |
| mode of action | protein synthesis | interferes |
| product line | BioReagent |
| Quality Level | 100 ![]() |
200 ![]() |
|
| SMILES string | O[C@H]1[C@H](O)[C@@H](CO) |
| technique(s) | cell culture | plant: suitable |
| Application: | Paromomycin, monomycin, is an aminoglycoside antibiotic used to select genetically transformed plants and plant cells. |
| Biochem/physiol Actions: | Antimicrobial spectrum: Gram-negative and Gram-positive bacteria, some protozoan species, and limited antihelminth. Mode of Action: Inhibits initiation and elongation during protein synthesis. |
| Biochem/physiol Actions: | Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death. |
| General description: | Chemical structure: aminoglycoside |
| Other Notes: | Keep container tightly closed in a dry and well-ventilated place |
| Packaging: | 5g,25g |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 10171502 |

